PhD Programs in Medicine
FOUR COURSES COVERING A WIDE VARIETY OF RESEARCH AREAS
We offer a diverse range of research areas within the Graduate School of Medicine. To help you identify a supervisor related to your research area you may like to explore the research interests of our academic staff.
Metabolic Control System
| Supervisor(s) | Research areas / topics |
| Prof. Atsuhiko Naito, MD, PhD | 1.Biology of non-mitotic cells |
| 2.Systems biology of the mechanism of cell-fate decision | |
| 3.Clinical studies using Artificial Intelligence/Machine Learning Model | |
| 4.Molecular mechanism for circadian clock; physiological ＆ medical roles | |
| 5.Chrono-adaptation systems synchronously responding to environmental stresses | |
| 6.Mathematical modeling of drug-induced cardiotoxicity | |
| 7.Translational Research of Congenital Heart Block |
| Supervisor(s) | Research areas / topics |
| Prof. Katsuhide Okunishi, MD, PhD | 1. Elucidation of characteristics and regulatory mechanisms of IL-5-producing Th2 cells |
| 2, Novel roles of the immune system in obesity | |
| 3. Novel pathophysiological roles of the secretion-regulatiing protein Rab27 and its effectors in disaeases | |
| 4. Role of alveolar epithelial cells in the recovery from lung injury | |
| 5. Elucidation of colorectal cancer development mechanisms mediated by inflammatory fibroblasts in the tumor | |
| 6. Investigation of metastatic cancer control mechanisms targeting the dynamics of stromal fibroblasts | |
| 7. Exploring the regulatory mechanisms of homeostasis mediated by cytokine IL-11 and its Application to disease treatment | |
| 8. Significance of cell death in allergy, obesity/diabetes, and cancer | |
| 9. Development of novel therapeutic strategies for diseases (based on 1-8 listed above) |
Currently not open
| Supervisor(s) | Research areas / topics |
| Prof. Tatsuya Morimoto, MD, PhD | 1. Elucidation of signaling pathways regulating heart failure onset |
| 2. Development of therapeutic strategies for heart failure using natural products | |
| 3. Identification and functional characterization of p300-interacting proteins | |
| 4. Elucidation of the mechanisms underlying heart failure onset mediated by epigenetic regulation | |
| 5. Elucidation of the molecular mechanisms of GATA4 activation | |
| 6. Investigation of the mechanisms underlying HFpEF and development of therapeutic strategies | |
| 7. Exploration of dipeptides as novel therapeutics for heart failure |
| Supervisor(s) | Research areas / topics |
| Prof. Takanori Ikeda, MD, PhD | 1. Prediction and Prevention of Sudden Cardiac Death Using Electrocardiographic Markers |
| 2. Electrophysiological Study Regarding Mechanisms on Occurrence of Tachyarrhythmias | |
| 3. Clinical Effect of Pharmacotherapy and Catheter ablation in atrial fibrillation | |
| 4. Clinical Pharmacological Research Regarding Efficacy of Cardiovascular Medicines | |
| 5. Clinical Assessment of Catheter Techniques and/or Implantable Devices in Cardiology | |
| 6. Clinical Evaluation Regarding Interventional Treatment in Coronary Artery Disease | |
| 7. Assessment Regarding Pathology and Treatment in Heart Failure and/or Pulmonary Hypertension | |
| 8．Assessment of Cardiovascular diseases Using Cardiac Imaging Modalities | |
| 9．Prognosis of Deep Venous Thrombosis and Pulmonary Thromboembolism | |
| Prof. Hidehiko Hara, MD, PhD | 1. Research on catheter treatment for structural heart disease |
| 2. Research on adult congenital heart disease, drugs and catheter treatment | |
| 3. Clinical research on drug treatment and catheter ablation for arrhythmia | |
| 4. Research on bradyarrhythmia and pacemakers | |
| 5. Research on diagnosis and treatment of heart failure | |
| 6. Research on the diagnosis and therapeutic effects of heart disease using echocardiography | |
| 7. Research on cardiomyopathy and valvular heart disease using cardiac MRI/CT | |
| 8. Research on catheter treatment for acute coronary syndrome | |
| 9. Research on arteriosclerosis and dyslipidemia | |
| 10. Research on diagnosis, drugs, and catheter treatment of pulmonary thromboembolism and pulmonary hypertension |
| Supervisor(s) | Research areas / topics |
| Prof. Mayumi Ishikawa, MD, PhD | 1. Research on various pathologies and treatment methods for diabetes |
| 2. Research on the pathophysiology of obesity-related diseases in severe obesity | |
| 3. Research on multifunctional insulin and its biology | |
| 4. Research on the analysis of the effects of placental growth hormone | |
| 5. Research on growth hormone and dementia | |
| Prof. Masahiro Ohira, MD, PhD | 1. Research on the pathogenesis of type 2 diabetes |
| 2. Research on the treatment of type 2 diabetes | |
| 3. Research on the relationship between type 2 diabetes and malignancy | |
| 4. Research on the prognosis of type 1 diabetes | |
| 5. Research on the relationship between adrenocorticosteroids and type 2 diabetes | |
| Prof. Atsuhito Saiki, MD, PhD | 1. Anti-atherosclerotic factor derived from subcutaneous fat |
| 2. Antioxidant effect of cholinesterase with C5 mutation | |
| 3. New diagnostic criteria for metabolic syndrome using ABSI | |
| 4. Fatty acid metabolism abnormalities in patients with severe obesity using 123I-BMIPP myocardial scintigraphy | |
| 5. ATGL gene or lipase activity abnormalities in obesity cardiomyopathy | |
| 6. Survey of bariatric and metabolic surgery (including mental health and nutrition) | |
| 7. Sub-analysis of J-SMART study (diabetes remission/relapse, children and elderly) | |
| 8. VAP-1, a novel atherosclerosis factor derived from visceral fat | |
| 9. A multi-faceted retrospective observational study of anti-obesity drugs |
| Supervisor(s) | Research areas / topics |
| Prof. Takahisa Matsuda, MD, PhD | 1. Research on diagnosis and treatment for gastrointestinal cancers |
| 2. Research on diagnosis and treatment for bilio-pancreatic diseases | |
| 3. Research on diagnosis and treatment for liver diseases | |
| 4. Research on recurrence of common bile duct stones | |
| 5. Research on inflammatory bowel disease | |
| 6. Research on gastrointestinal motility | |
| 7. Research on Helicobacter pylori | |
| 8. Research on peptic ulcer | |
| 9. Research on gastrointestinal cancer screening | |
| 10. Research on the development of endoscope-related equipments | |
| Prof. Katsuyoshi Matsuoka, MD, PhD | 1. Studies utilizing prospective cohorts of patients with inflammatory bowel disease |
| 2. Studies on the therapeutic effects of drugs for inflammatory bowel disease | |
| 3. Studies on the pathogenesis of inflammatory bowel disease | |
| 4. Studies on the search of biomarkers in inflammatory bowel disease |
| Supervisor(s) | Research areas / topics |
| Prof. Yuichiro Otsuka, MD, PhD | 1. Research on improvement of surgical outcome for Hepatocellular carcinoma |
| 2. Research on improvement of surgical outcome for Metastatic tumor from Colo-rectal cancer | |
| 3. Research on standardization of minimally invasive surgery for liver disease | |
| 4. Research on improvement of surgical outcome for Biliary cancer | |
| 5. Research on standardization of minimally invasive surgery for Biliary disease | |
| 6. Research on improvement of surgical outcome for Pancreatic cancer | |
| 7. Research on standardization of minimally invasive surgery for Pancreatic disease | |
| Prof. Yoshihisa Saida, MD, PhD | 1. Digestive Surgery: Stomach, Small Intestine, Colon and Rectum, Surgical Treatment and Chemotherapy of Colorectal Cancer |
| 2. Minimal-invasive treatment: endoscopic treatment, laparoscopic surgery, laparoscopiy endoscopy combination suregry | |
| 3.Digestive endoscopy: Digestive endoscopy diagnosis, endoscopic treatment, colonic stent, intraoperative endoscopy. antibacterial therapy, nosocomial infection | |
| 4. Infectious disease: postoperative infection,antibacterial therapy, nosocomial infection | |
| 5. Non-smoking instruction | |
| Prof. Manabu Watanabe, MD, PhD | 1. Hepato-Biliary-Pancreatic surgery |
| 2. Endoscopic surgery, Reduced port surgery | |
| 3. Postoperative infection: Surgical site infection, Remote infection, Perioperative infection control | |
| 4. Surveillance of infectious complications following gastroenterological surgery | |
| 5. Laparoscopic cholecystectomy for acute cholecystitis | |
| 6. Metagenomic analysis for acute cholangitis | |
| 7. Multimodal imaging of cancerous regions utilizing spectral X-ray CT and 7T-MRI | |
| Prof. Kenji Kawada, MD, PhD | 1. Research to improve surgical treatment for colorectal cancer |
| 2. Minimally invasive surgical treatments: robotic surgery, laparoscopic surgery | |
| 3.Research toward standardizing minimally invasive surgery for rectal cancer | |
| 4.Development of a tool to predict surgical risks in rectal cancer surgery | |
| 5.Research to improve quality of life (bowel, urinary, and sexual functions) following rectal cancer surgery | |
| 6.Therapeutic strategies targeting myeloid cells in the tumor microenvironment |
| Supervisor(s) | Research areas / topics |
| Prof. Takeshiro Fujii, MD, PhD | 1. New deivce of frozen elephant trunk for thoracic aortic disease |
| 2. Hemodynamic assessment of aortic remodeling after arch aortic stent graft implantation. | |
| 3. Development of a New Sten Graft Using Numerical Fluid Analysis with 4DflowMRI | |
| 4. Analysis of non-invasive sutureless valve for aortic valve disease | |
| 5. Analysis of no-touch saphenous vein graft structure for coronary aorta bypass grafting | |
| 6. Intracardiac Three-Dimensional Image as Surgical Decision-Making Tool of Congenital Heatr Disease | |
| 7. Effecst of coronary artery bypass grafting with multiple arterial grafts. | |
| 8. Clinical effect of mitral valve plasty in patients who undergo ventricular assist device implantation. | |
| 9. New therapeutic strategy using ventricular assist devices in patients with severe heart failure | |
| Prof. Mizuno Tomohiro, MD, PhD | 1. Estimation on mid-term and long-term effects of multi-arterial grafts in off-pump conary artery bypass grafting |
| 2. The righ gastroepiopuloic artery as a free graft in CABG: Evaluation of reconstruction sites and long-term prognosis | |
| 3. Verificatoin of the usefulness of on-pump beating CABG for acute coronary syndrome | |
| 4. Evaluation of off-pump CABG using percutaneous left ventricular assist catheter devices in patients with deteriolated LV function | |
| 5. Establishing a new ethic for permanent use (Destination Therapy) of implantable left ventricular assist devices | |
| 6. Surgical techniques of mitral valve repair in minimally invasive cardiac surgery (MICS) | |
| 7. Surgical innovations to improve the safety of minimally invasive cardiac surgery (MICS) | |
| 8. Can Lactococcus lactis strain Plasma prevent infectious complications in cardiac surgery for dialysis patients? | |
| 9. To investigation of risk factors for post-cardiac surgery infection complications in dialysis patients | |
| 10. Evaluation of the efficacy and prognosis of stent graft treatment for type B aortic dissection. | |
| Prof. Numata Satoshi, MD, PhD | 1. Aortic arch blood flow analysis using computational flow simulation |
| 2. Valve function analysis after mitral valve repair using exercise stress echocardiography | |
| 3. Evaluation of ideal flexibility of the band for mitral valve repari | |
| 4. Evaluation of temperature managemant for aortic arch repair using antegrade cerebral perfusion | |
| 5. Comparison between off-pump and on-pump coronary artery bypass grafting | |
| 6. Histological and computational fluid dynamical analysis of mechanizm of acute aortic dissection | |
| 7. Evaluation of ideal anastomosis of coronary artery bypass grafting | |
| 8. Evaluation of ideal cardiopulmnary bypass flow management of thoracoscopic assisted mitral valve surgery | |
| 9. Development of alternative method for left ventricular aneurysm repair |
| Supervisor(s) | Research areas / topics |
| Prof. Masahiko Nakata, MD, PhD | 1. Study of evaluation for fetal cardiac function |
| 2. Study of pathological mechanism in twin-to-twin transfusion syndrome | |
| 3. Study of pathological mechanism in fetal growth restriction | |
| 4. Study of organ development and the dysfunction in the human fetus | |
| 5. Study for maternal cardiovascular dynamics in pregnancy | |
| Prof. Yukiko Katagiri, MD, PhD | 1. Research on early embryogenesis |
| 2. Research on implantation environment | |
| 3. Research on bacterial flora and fertility | |
| 4. Study on organic diseases of the internal genitalia and fertility | |
| 5. Research on the effects of reproductive medicine on the fetus and placenta | |
| 6. Study for oncofertility | |
| Prof. Kenbun Sone, MD, PhD | 1. Development of Molecular Targeted Therapeutics Focusing on Histone Modifications in Gynecologic Cancers |
| 2. Development of Medical Devices Using Deep Learning for Gynecologic Cancers | |
| 3. Research on Cancer Reversion in Gynecologic Cancers | |
| 4. Development of an Optimal Treatment Decision-Making Model for Elderly Patients with Gynecologic Cancers | |
| 5. Development of a Surgical Navigation System Using Deep Learning | |
| 6. Elucidation of the Mechanisms Underlying Carcinogenesis and Progression of Gynecologic Cancers Through Epigenomic Regulation | |
| Prof. Kyoko Tanaka, MD, PhD | 1. Analysis of early genes in HPV maintenance replication |
| 2. Functional analysis of low-risk HPV and high-risk HPV for p53 | |
| 3. The relationship between prognosis of CIN2 and expression of HPV E4 | |
| 4. Study on the effectiveness of laser vaporization for CIN3 | |
| 5. Study on the safety of radical trachelectomy for early stage of cervical cancer |
| Supervisor(s) | Research areas / topics |
| Prof. Naomi Shimizu, MD, PhD | 1. Research on the relationship between chemotherapy and atherosclerosis |
| 2. Research on the relationship between the progression of myelodysplastic syndrome and oxidative stress | |
| 3. New production mechanism of presepsin as a septic infection marker | |
| 4. Hematological malignancy and soluble LR11 | |
| 5. Research of the factors related with the prognosis of malignant lymphoma | |
| 6. The pathology of vitamin B6 deficiency |
| Supervisor(s) | Research areas / topics |
| Prof. Yosuke Sasaki, MD, PhD | 1. Study on the diagnosis of vitamin B12 deficiency by 13C propionate breath test |
| 2. Study on the diagnosis of prostate cancer using exhaled aldehydes | |
| 3. Clinical study on high eGFR | |
| 4. Epidemiological studies on chronic kidney disease and renal anemia | |
| 5. Epidemiological studies on the risk of cardiovascular disease due to asymptomatic hyperuricemia and therapeutic intervention | |
| 6. Reconstruction and validation of a predictive model to estimate the likelihood of infective endocarditis from cases of fever of unknown origin | |
| 7. Evaluation of the usefulness of the Hoesch reagent as an initial screening test for acute hepatic porphyria | |
| 8. Exploring the clinical practice and prevalence of hereditary angioedema in patients visiting hospital general medicine departments in Japan | |
| 9. Study on analysis of pharyngeal images using machine learning in patients with fever and airway symptoms |
| Supervisor(s) | Research areas / topics |
| Prof. Ken Sakai, MD, PhD | 1. Bioelectrical Impedance Analysis (clinical study) |
| 2. Peritoneal Function and Pathology for Patients with PD/HD Combination Therapy (clinical study) | |
| 3. Study for Renal Transplant Recipients/Donors: Biopsy-based Long-term Prognosis and Recurrence Nephritis | |
| 4. CNI Renal Toxicity Analysis and Periodical Renal Biopsy Findings | |
| 5. Nutritional Status for Patients with Low-Protein Diet Regimen | |
| 6. Dialysis Reintroduction after Renal Transplantation | |
| 7. Growth in Children with Renal Failure after Renal Transplantation | |
| 8. Chronic antibody-mediated rejection with positive DSA | |
| 9. Proliferative T cell profile analysis | |
| 10. Regeneration of tubular epithelial cells in kidney graft | |
| Prof. Yuko Hamasaki, MD, PhD | 1. Trends in EBV-DNA after pediatric kidney transplantation |
| 2. Sex hormone changes and growth | |
| 3. Quality of life study | |
| 4. Epitope analysis in pediatric kidney transplantation | |
| 5. Developmental evaluation | |
| 6. Transitional care support | |
| Prof. Nobuhiko Joki, MD, PhD | 1. Potassium homeostasis in chronic kidney disease |
| 2. Phosphorus metabolism and myocardial repolarization | |
| 3. Uremic milieu and oxygen supply-demand balance | |
| 4. Uric acid and CKD progression | |
| 5. Sudden cardiac death risk in kidney disease | |
| 6. Body morphometry and kidney health | |
| 7. Frailty in chronic kidney disease | |
| 8. Polycystic kidney disease therapeutics | |
| Prof. Yasushi Ohashi, MD, PhD | 1. Management of CKD across life stages |
| 2. Fluid imbalance and accumulation | |
| 3. Calcium balance and vascular calcification | |
| 4. Dry weight assessment development | |
| 5. DRYFIT scoring system | |
| 6. Body fluid distribution mapping | |
| 7. ADL recovery after illness |
| Supervisor(s) | Research areas / topics |
| Prof. Takahisa Matsuda, MD, PhD | 1. Clinical research on optimal treatment selection for early-stage gastrointestinal cancer |
| 2. Study on treatment outcomes and therapeutic strategies for advanced colorectal cancer in the elderly | |
| 3. Research on the application of AI and quality assurance in endoscopic imaging diagnosis of gastrointestinal diseases | |
| 4. Study on prediction of treatment efficacy using tissue and genetic biomarkers | |
| 5. Prospective cohort study on long-term outcomes after endoscopic treatment for early-stage gastrointestinal cancer | |
| 6. Research contributing to risk stratification of pancreatic cancer | |
| Prof. Manabu Watanabe, MD, PhD | 1. Hepato-Biliary-Pancreatic surgery |
| 2. Endoscopic surgery, reduced-port surgery | |
| 3. Multimodal imaging of cancerous regions utilizing spectral X-ray CT and 7T-MRI |
| Supervisor(s) | Research areas / topics |
| Prof. Atsuhiko Naito, MD, PhD | 1.Biology of non-mitotic cells |
| 2.Systems biology of the mechanism of cell-fate decision | |
| 3.Clinical studies using Artificial Intelligence/Machine Learning Model | |
| 4.Molecular mechanism for circadian clock; physiological ＆ medical roles | |
| 5.Chrono-adaptation systems synchronously responding to environmental stresses | |
| 6.Mathematical modeling of drug-induced cardiotoxicity | |
| 7.Translational Research of Congenital Heart Block |
| Supervisor(s) | Research areas / topics |
| Prof. Katsuhide Okunishi, MD, PhD | 1. Elucidation of characteristics and regulatory mechanisms of IL-5-producing Th2 cells |
| 2, Novel roles of the immune system in obesity | |
| 3. Novel pathophysiological roles of the secretion-regulatiing protein Rab27 and its effectors in disaeases | |
| 4. Role of alveolar epithelial cells in the recovery from lung injury | |
| 5. Elucidation of colorectal cancer development mechanisms mediated by inflammatory fibroblasts in the tumor | |
| 6. Investigation of metastatic cancer control mechanisms targeting the dynamics of stromal fibroblasts | |
| 7. Exploring the regulatory mechanisms of homeostasis mediated by cytokine IL-11 and its Application to disease treatment | |
| 8. Significance of cell death in allergy, obesity/diabetes, and cancer | |
| 9. Development of novel therapeutic strategies for diseases (based on 1-8 listed above) |
Currently not open
| Supervisor(s) | Research areas / topics |
| Prof. Tatsuya Morimoto, MD, PhD | 1. Elucidation of signaling pathways regulating heart failure onset |
| 2. Development of therapeutic strategies for heart failure using natural products | |
| 3. Identification and functional characterization of p300-interacting proteins | |
| 4. Elucidation of the mechanisms underlying heart failure onset mediated by epigenetic regulation | |
| 5. Elucidation of the molecular mechanisms of GATA4 activation | |
| 6. Investigation of the mechanisms underlying HFpEF and development of therapeutic strategies | |
| 7. Exploration of dipeptides as novel therapeutics for heart failure |
| Supervisor(s) | Research areas / topics |
| Prof. Takanori Ikeda, MD, PhD | 1. Prediction and Prevention of Sudden Cardiac Death Using Electrocardiographic Markers |
| 2. Electrophysiological Study Regarding Mechanisms on Occurrence of Tachyarrhythmias | |
| 3. Clinical Effect of Pharmacotherapy and Catheter ablation in atrial fibrillation | |
| 4. Clinical Pharmacological Research Regarding Efficacy of Cardiovascular Medicines | |
| 5. Clinical Assessment of Catheter Techniques and/or Implantable Devices in Cardiology | |
| 6. Clinical Evaluation Regarding Interventional Treatment in Coronary Artery Disease | |
| 7. Assessment Regarding Pathology and Treatment in Heart Failure and/or Pulmonary Hypertension | |
| 8．Assessment of Cardiovascular diseases Using Cardiac Imaging Modalities | |
| 9．Prognosis of Deep Venous Thrombosis and Pulmonary Thromboembolism | |
| Prof. Hidehiko Hara, MD, PhD | 1. Research on catheter treatment for structural heart disease |
| 2. Research on adult congenital heart disease, drugs and catheter treatment | |
| 3. Clinical research on drug treatment and catheter ablation for arrhythmia | |
| 4. Research on bradyarrhythmia and pacemakers | |
| 5. Research on diagnosis and treatment of heart failure | |
| 6. Research on the diagnosis and therapeutic effects of heart disease using echocardiography | |
| 7. Research on cardiomyopathy and valvular heart disease using cardiac MRI/CT | |
| 8. Research on catheter treatment for acute coronary syndrome | |
| 9. Research on arteriosclerosis and dyslipidemia | |
| 10. Research on diagnosis, drugs, and catheter treatment of pulmonary thromboembolism and pulmonary hypertension |
| Supervisor(s) | Research areas / topics |
| Prof. Mayumi Ishikawa, MD, PhD | 1. Research on various pathologies and treatment methods for diabetes |
| 2. Research on the pathophysiology of obesity-related diseases in severe obesity | |
| 3. Research on multifunctional insulin and its biology | |
| 4. Research on the analysis of the effects of placental growth hormone | |
| 5. Research on growth hormone and dementia | |
| Prof. Masahiro Ohira, MD, PhD | 1. Research on the pathogenesis of type 2 diabetes |
| 2. Research on the treatment of type 2 diabetes | |
| 3. Research on the relationship between type 2 diabetes and malignancy | |
| 4. Research on the prognosis of type 1 diabetes | |
| 5. Research on the relationship between adrenocorticosteroids and type 2 diabetes | |
| Prof. Atsuhito Saiki, MD, PhD | 1. Anti-atherosclerotic factor derived from subcutaneous fat |
| 2. Antioxidant effect of cholinesterase with C5 mutation | |
| 3. New diagnostic criteria for metabolic syndrome using ABSI | |
| 4. Fatty acid metabolism abnormalities in patients with severe obesity using 123I-BMIPP myocardial scintigraphy | |
| 5. ATGL gene or lipase activity abnormalities in obesity cardiomyopathy | |
| 6. Survey of bariatric and metabolic surgery (including mental health and nutrition) | |
| 7. Sub-analysis of J-SMART study (diabetes remission/relapse, children and elderly) | |
| 8. VAP-1, a novel atherosclerosis factor derived from visceral fat | |
| 9. A multi-faceted retrospective observational study of anti-obesity drugs |
| Supervisor(s) | Research areas / topics |
| Prof. Takahisa Matsuda, MD, PhD | 1. Research on diagnosis and treatment for gastrointestinal cancers |
| 2. Research on diagnosis and treatment for bilio-pancreatic diseases | |
| 3. Research on diagnosis and treatment for liver diseases | |
| 4. Research on recurrence of common bile duct stones | |
| 5. Research on inflammatory bowel disease | |
| 6. Research on gastrointestinal motility | |
| 7. Research on Helicobacter pylori | |
| 8. Research on peptic ulcer | |
| 9. Research on gastrointestinal cancer screening | |
| 10. Research on the development of endoscope-related equipments | |
| Prof. Katsuyoshi Matsuoka, MD, PhD | 1. Studies utilizing prospective cohorts of patients with inflammatory bowel disease |
| 2. Studies on the therapeutic effects of drugs for inflammatory bowel disease | |
| 3. Studies on the pathogenesis of inflammatory bowel disease | |
| 4. Studies on the search of biomarkers in inflammatory bowel disease |
| Supervisor(s) | Research areas / topics |
| Prof. Yuichiro Otsuka, MD, PhD | 1. Research on improvement of surgical outcome for Hepatocellular carcinoma |
| 2. Research on improvement of surgical outcome for Metastatic tumor from Colo-rectal cancer | |
| 3. Research on standardization of minimally invasive surgery for liver disease | |
| 4. Research on improvement of surgical outcome for Biliary cancer | |
| 5. Research on standardization of minimally invasive surgery for Biliary disease | |
| 6. Research on improvement of surgical outcome for Pancreatic cancer | |
| 7. Research on standardization of minimally invasive surgery for Pancreatic disease | |
| Prof. Yoshihisa Saida, MD, PhD | 1. Digestive Surgery: Stomach, Small Intestine, Colon and Rectum, Surgical Treatment and Chemotherapy of Colorectal Cancer |
| 2. Minimal-invasive treatment: endoscopic treatment, laparoscopic surgery, laparoscopiy endoscopy combination suregry | |
| 3.Digestive endoscopy: Digestive endoscopy diagnosis, endoscopic treatment, colonic stent, intraoperative endoscopy. antibacterial therapy, nosocomial infection | |
| 4. Infectious disease: postoperative infection,antibacterial therapy, nosocomial infection | |
| 5. Non-smoking instruction | |
| Prof. Manabu Watanabe, MD, PhD | 1. Hepato-Biliary-Pancreatic surgery |
| 2. Endoscopic surgery, Reduced port surgery | |
| 3. Postoperative infection: Surgical site infection, Remote infection, Perioperative infection control | |
| 4. Surveillance of infectious complications following gastroenterological surgery | |
| 5. Laparoscopic cholecystectomy for acute cholecystitis | |
| 6. Metagenomic analysis for acute cholangitis | |
| 7. Multimodal imaging of cancerous regions utilizing spectral X-ray CT and 7T-MRI | |
| Prof. Kenji Kawada, MD, PhD | 1. Research to improve surgical treatment for colorectal cancer |
| 2. Minimally invasive surgical treatments: robotic surgery, laparoscopic surgery | |
| 3.Research toward standardizing minimally invasive surgery for rectal cancer | |
| 4.Development of a tool to predict surgical risks in rectal cancer surgery | |
| 5.Research to improve quality of life (bowel, urinary, and sexual functions) following rectal cancer surgery | |
| 6.Therapeutic strategies targeting myeloid cells in the tumor microenvironment |
| Supervisor(s) | Research areas / topics |
| Prof. Takeshiro Fujii, MD, PhD | 1. New deivce of frozen elephant trunk for thoracic aortic disease |
| 2. Hemodynamic assessment of aortic remodeling after arch aortic stent graft implantation. | |
| 3. Development of a New Sten Graft Using Numerical Fluid Analysis with 4DflowMRI | |
| 4. Analysis of non-invasive sutureless valve for aortic valve disease | |
| 5. Analysis of no-touch saphenous vein graft structure for coronary aorta bypass grafting | |
| 6. Intracardiac Three-Dimensional Image as Surgical Decision-Making Tool of Congenital Heatr Disease | |
| 7. Effecst of coronary artery bypass grafting with multiple arterial grafts. | |
| 8. Clinical effect of mitral valve plasty in patients who undergo ventricular assist device implantation. | |
| 9. New therapeutic strategy using ventricular assist devices in patients with severe heart failure | |
| Prof. Mizuno Tomohiro, MD, PhD | 1. Estimation on mid-term and long-term effects of multi-arterial grafts in off-pump conary artery bypass grafting |
| 2. The righ gastroepiopuloic artery as a free graft in CABG: Evaluation of reconstruction sites and long-term prognosis | |
| 3. Verificatoin of the usefulness of on-pump beating CABG for acute coronary syndrome | |
| 4. Evaluation of off-pump CABG using percutaneous left ventricular assist catheter devices in patients with deteriolated LV function | |
| 5. Establishing a new ethic for permanent use (Destination Therapy) of implantable left ventricular assist devices | |
| 6. Surgical techniques of mitral valve repair in minimally invasive cardiac surgery (MICS) | |
| 7. Surgical innovations to improve the safety of minimally invasive cardiac surgery (MICS) | |
| 8. Can Lactococcus lactis strain Plasma prevent infectious complications in cardiac surgery for dialysis patients? | |
| 9. To investigation of risk factors for post-cardiac surgery infection complications in dialysis patients | |
| 10. Evaluation of the efficacy and prognosis of stent graft treatment for type B aortic dissection. | |
| Prof. Numata Satoshi, MD, PhD | 1. Aortic arch blood flow analysis using computational flow simulation |
| 2. Valve function analysis after mitral valve repair using exercise stress echocardiography | |
| 3. Evaluation of ideal flexibility of the band for mitral valve repari | |
| 4. Evaluation of temperature managemant for aortic arch repair using antegrade cerebral perfusion | |
| 5. Comparison between off-pump and on-pump coronary artery bypass grafting | |
| 6. Histological and computational fluid dynamical analysis of mechanizm of acute aortic dissection | |
| 7. Evaluation of ideal anastomosis of coronary artery bypass grafting | |
| 8. Evaluation of ideal cardiopulmnary bypass flow management of thoracoscopic assisted mitral valve surgery | |
| 9. Development of alternative method for left ventricular aneurysm repair |
| Supervisor(s) | Research areas / topics |
| Prof. Masahiko Nakata, MD, PhD | 1. Study of evaluation for fetal cardiac function |
| 2. Study of pathological mechanism in twin-to-twin transfusion syndrome | |
| 3. Study of pathological mechanism in fetal growth restriction | |
| 4. Study of organ development and the dysfunction in the human fetus | |
| 5. Study for maternal cardiovascular dynamics in pregnancy | |
| Prof. Yukiko Katagiri, MD, PhD | 1. Research on early embryogenesis |
| 2. Research on implantation environment | |
| 3. Research on bacterial flora and fertility | |
| 4. Study on organic diseases of the internal genitalia and fertility | |
| 5. Research on the effects of reproductive medicine on the fetus and placenta | |
| 6. Study for oncofertility | |
| Prof. Kenbun Sone, MD, PhD | 1. Development of Molecular Targeted Therapeutics Focusing on Histone Modifications in Gynecologic Cancers |
| 2. Development of Medical Devices Using Deep Learning for Gynecologic Cancers | |
| 3. Research on Cancer Reversion in Gynecologic Cancers | |
| 4. Development of an Optimal Treatment Decision-Making Model for Elderly Patients with Gynecologic Cancers | |
| 5. Development of a Surgical Navigation System Using Deep Learning | |
| 6. Elucidation of the Mechanisms Underlying Carcinogenesis and Progression of Gynecologic Cancers Through Epigenomic Regulation | |
| Prof. Kyoko Tanaka, MD, PhD | 1. Analysis of early genes in HPV maintenance replication |
| 2. Functional analysis of low-risk HPV and high-risk HPV for p53 | |
| 3. The relationship between prognosis of CIN2 and expression of HPV E4 | |
| 4. Study on the effectiveness of laser vaporization for CIN3 | |
| 5. Study on the safety of radical trachelectomy for early stage of cervical cancer |
| Supervisor(s) | Research areas / topics |
| Prof. Naomi Shimizu, MD, PhD | 1. Research on the relationship between chemotherapy and atherosclerosis |
| 2. Research on the relationship between the progression of myelodysplastic syndrome and oxidative stress | |
| 3. New production mechanism of presepsin as a septic infection marker | |
| 4. Hematological malignancy and soluble LR11 | |
| 5. Research of the factors related with the prognosis of malignant lymphoma | |
| 6. The pathology of vitamin B6 deficiency |
| Supervisor(s) | Research areas / topics |
| Prof. Yosuke Sasaki, MD, PhD | 1. Study on the diagnosis of vitamin B12 deficiency by 13C propionate breath test |
| 2. Study on the diagnosis of prostate cancer using exhaled aldehydes | |
| 3. Clinical study on high eGFR | |
| 4. Epidemiological studies on chronic kidney disease and renal anemia | |
| 5. Epidemiological studies on the risk of cardiovascular disease due to asymptomatic hyperuricemia and therapeutic intervention | |
| 6. Reconstruction and validation of a predictive model to estimate the likelihood of infective endocarditis from cases of fever of unknown origin | |
| 7. Evaluation of the usefulness of the Hoesch reagent as an initial screening test for acute hepatic porphyria | |
| 8. Exploring the clinical practice and prevalence of hereditary angioedema in patients visiting hospital general medicine departments in Japan | |
| 9. Study on analysis of pharyngeal images using machine learning in patients with fever and airway symptoms |
| Supervisor(s) | Research areas / topics |
| Prof. Ken Sakai, MD, PhD | 1. Bioelectrical Impedance Analysis (clinical study) |
| 2. Peritoneal Function and Pathology for Patients with PD/HD Combination Therapy (clinical study) | |
| 3. Study for Renal Transplant Recipients/Donors: Biopsy-based Long-term Prognosis and Recurrence Nephritis | |
| 4. CNI Renal Toxicity Analysis and Periodical Renal Biopsy Findings | |
| 5. Nutritional Status for Patients with Low-Protein Diet Regimen | |
| 6. Dialysis Reintroduction after Renal Transplantation | |
| 7. Growth in Children with Renal Failure after Renal Transplantation | |
| 8. Chronic antibody-mediated rejection with positive DSA | |
| 9. Proliferative T cell profile analysis | |
| 10. Regeneration of tubular epithelial cells in kidney graft | |
| Prof. Yuko Hamasaki, MD, PhD | 1. Trends in EBV-DNA after pediatric kidney transplantation |
| 2. Sex hormone changes and growth | |
| 3. Quality of life study | |
| 4. Epitope analysis in pediatric kidney transplantation | |
| 5. Developmental evaluation | |
| 6. Transitional care support | |
| Prof. Nobuhiko Joki, MD, PhD | 1. Potassium homeostasis in chronic kidney disease |
| 2. Phosphorus metabolism and myocardial repolarization | |
| 3. Uremic milieu and oxygen supply-demand balance | |
| 4. Uric acid and CKD progression | |
| 5. Sudden cardiac death risk in kidney disease | |
| 6. Body morphometry and kidney health | |
| 7. Frailty in chronic kidney disease | |
| 8. Polycystic kidney disease therapeutics | |
| Prof. Yasushi Ohashi, MD, PhD | 1. Management of CKD across life stages |
| 2. Fluid imbalance and accumulation | |
| 3. Calcium balance and vascular calcification | |
| 4. Dry weight assessment development | |
| 5. DRYFIT scoring system | |
| 6. Body fluid distribution mapping | |
| 7. ADL recovery after illness |
| Supervisor(s) | Research areas / topics |
| Prof. Takahisa Matsuda, MD, PhD | 1. Clinical research on optimal treatment selection for early-stage gastrointestinal cancer |
| 2. Study on treatment outcomes and therapeutic strategies for advanced colorectal cancer in the elderly | |
| 3. Research on the application of AI and quality assurance in endoscopic imaging diagnosis of gastrointestinal diseases | |
| 4. Study on prediction of treatment efficacy using tissue and genetic biomarkers | |
| 5. Prospective cohort study on long-term outcomes after endoscopic treatment for early-stage gastrointestinal cancer | |
| 6. Research contributing to risk stratification of pancreatic cancer | |
| Prof. Manabu Watanabe, MD, PhD | 1. Hepato-Biliary-Pancreatic surgery |
| 2. Endoscopic surgery, reduced-port surgery | |
| 3. Multimodal imaging of cancerous regions utilizing spectral X-ray CT and 7T-MRI |
Integrative Biosystem
| Supervisor(s) | Research areas / topics |
| Prof. Tomokazu Kawashima, MD, PhD | 1. Topographic anatomy of the cardiac conduction system |
| 2. Functional anatomy and histology of the cardiovascular structures | |
| 3. Clinical anatomy of the abdominal and pelvic autonomic nervous system | |
| 4. Integrated anatomy and evolutionary morphology of the limb plexus | |
| 5. Visualization of human internal fine structures using multimodal imaging |
| Supervisor(s) | Research areas / topics |
| Prof. Hiromasa Funato, MD, PhD | 1. Functional neuroanatomy for sleep/wakefulness |
| 2. Molecular mechanism regulating sleep/wakefulness | |
| 3. Functional neuroanatomy of the preoptic area | |
| 4. Neural circuitry regulating innate behaviors |
| Supervisor(s) | Research areas / topics |
| Prof. Satomi Adachi-Akahane, MD, PhD | 1. Integrative and systems physiology of regulatory mechanisms underlying homeostasis of cardiac function: Elucidation of the molecular basis for regulation via inter-organ networks consisting of heart, digestive system, adipose tissue, kidney, skeletal muscle, and autonomic nervous system |
| 2. Pathophysiology of cardiac diseases caused by metabolic dysregulation | |
| 3. Molecular basis of sensing and regulation of organ function focusing on voltage-gated calcium channels | |
| 4. Molecular mechanisms of lipid metabolism regulation and related disease onset (e.g., NASH) | |
| 5. Systems physiology of fine-tuning cell signaling dynamics: Integrated understanding using molecular imaging and computational science |
Currently not available
| Supervisor(s) | Research areas / topics |
| Prof.Osamu Kano, MD, PhD | 1. Identifying the new biomarker in neurodegenerative disease |
| 2. Identifying the pathogenesis of ALS | |
| 3. Robot-assisted training using Hybrid assistive Limb for neurodegenerative patients | |
| 4. Analyzing the cerebral infarction in three dimensions | |
| 5. New functional rating score for primarily lateral sclerosis patients | |
| 6. Development the new diagnostic tool using artificial intelligence |
| Supervisor(s) | Research areas / topics |
| Prof. Nobuo Sugo, MD, PhD | 1. Study of nuclear medicine for diagnosis of brain tumors |
| 2. Study of surgical approach to skull base tumors | |
| 3. Study on hardness of brain tumors | |
| 4. Study on 3D fusion imaging of the brain | |
| 5. Study on endovascular surgery for cerebral aneurysm | |
| 6. Study of surgical treatment for carotid artery stenosis | |
| 7. Study of neurosurgical simulation | |
| 8. Study of brain disease using rapid prototyping models by 3D printing | |
| 9. Study of intraoperative cerebral blood flow using laser speckle flowgraphy (LSFG) | |
| 10. Molding of 3D models for neuroendoscopic surgery and surgical practice | |
| Prof. Norihiko Saito, MD, PhD | 1. Analysis of the tumor immune microenvironment and development of immunotherapies in malignant glioma |
| 2. Development of molecular targeted therapies based on glioma stem cell subtypes | |
| 3. Evaluation of tumor treating fields combined with chemotherapy for glioblastoma | |
| 4. Functional preservation strategies using awake craniotomy | |
| 5. Clinical evaluation of minimally invasive neuroendoscopic-assisted tumor resection | |
| 6. Investigation of antitumor effects of aromatic compounds | |
| 7. Control of peritumoral microenvironment in tumor invasion | |
| 8. Hemodynamic changes after flow diverter stent treatment | |
| 9. Use of 4D-perfusion imaging in thrombectomy eligibility | |
| 10. Novel therapy for cerebral vasospasm after subarachnoid hemorrhage | |
| Prof. Masaaki Nemoto, MD, PhD | 1. Study of subarachnoid hemorrhage with intracerebral hematoma |
| 2. Study of subarachnoid hemorrhage in elderly patients | |
| 3. Study of germinal matrix hemorrhage in extremely low-birth-weight infants | |
| 4. Clinical study of intracranial hypotension syndrome | |
| 5. Study of deep brain stimulation (DBS) for Parkinson’s disease | |
| 6. Study on development of delirium in neurosurgical disease |
| Supervisor(s) | Research areas / topics |
| Prof. Hiroshi Takahashi, MD, PhD | 1. Study on the mechanism of development of low back pain |
| 2. Study on quantitative evaluation of surgical stress | |
| 3. Regenerative medicine of bone and cartilage | |
| 4. Study on the diagnosis and treatment of articular infectious disease | |
| 5. Study on low-invasive spinal surgery | |
| 6. Study on a new treatment method for spinal canal stenosis | |
| 7. Study on the development of new treatment method for spinal deformity | |
| 8. Study on the cause of ossification of the posterior longitudinal ligament | |
| 9. Elucidation of the pathology of osteoporosis | |
| Prof. Osahiko Tsuji, MD, PhD | 1. Study on bone microstructure in total joint replacement |
| 2. Study on the risk of imminent fracture in osteoporotic vertebral fractures | |
| 3. Research on the prevention of SSI in orthopedic surgery | |
| 4. Research on postoperative pain in spinal and spinal cord disorders | |
| 5. Study on reducing radiation exposure to surgeons during intraoperative fluoroscopy | |
| 6. Study on imaging differential diagnosis of spinal cord tumors | |
| Prof. Koichi Nakagawa, MD, PhD | 1. Research on pathology and treatments of rheumatoid arthritis |
| 2. Development of a newly designed artificial knee joint | |
| 3. Research on regenerative medicine for articular cartilage | |
| 4. Molecular biological research of articular cartilage metabolism | |
| 5. Research on surgical treatments of ligament injuries of the knee | |
| 6. Research on minimally invasive spinal surgeries | |
| 7. Research on mechanisms of joint pain and assessment tools | |
| 8. Research on bone metabolism and osteoporosis | |
| 9. Research on diagnosis and treatments of spinal cord injury |
| Supervisor(s) | Research areas / topics |
| Prof. Akihiro Ogino, MD, PhD | 1. Research on intractable wound treatment |
| 2. Evaluation using blood flow visualization and digitization in flap reconstructive surgery | |
| 3. Intraoperative repositioning assessment using a navigation system in facial fractures | |
| 4. Evaluation of navigation-assisted bone osteotomy for malunited fractures | |
| 5. Verification of timing for distant flap separation by longitudinal blood flow evaluation | |
| 6. Research on negative pressure wound therapy | |
| 7. Comparative study of nanosecond and picosecond lasers for pigmented skin diseases | |
| 8. Research on therapeutic effects of smile reconstruction for facial paralysis |
Currently not open
| Supervisor(s) | Research areas / topics |
| Prof. Yoshimasa Takeda, MD, PhD | 1. Development of intraischemic hypothermia during cardiac arrest |
| 2. Research on quantitative evaluation of PONV | |
| 3. Investigation of stimulation parameters in electroconvulsive therapy | |
| 4. Development of an effective chest compression technique | |
| 5. Anatomical study of airway management | |
| Porf. Takayuki Kitamura, MD, PhD | 1. Optimization of perioperative glycemic control in patients undergoing cardiac surgery |
| 2. Optimization of anesthetic management for patients with inflammatory bowel disease |
| Supervisor(s) | Research areas / topics |
| Prof. Kota Wada, MD, PhD | 1. Research for refractory rhinosinusitis |
| 2. Research on the relationship between sinus function and sleep | |
| 3. Research on regeneration of nasal and sinus mucosa | |
| 4. Research on refractory rhinosinusitis using proteome analysis | |
| Prof. Mamoru Yoshikawa, MD, PhD | 1. Refractory factors in chronic rhinosinusitis |
| 2. Novel therapy in severe allergic rhinitis | |
| 3. Pathogenesis of allergic fungal rhinosinusitis (AFRS) | |
| 4. Pathogenesis of hearing impairment | |
| 5. New diagnostic method for obstructive sleep apnea (OSA) | |
| Prof. Munetaka Ushio, MD, PhD | 1. Equilibrium control by electrical stimulation: new approach for bilateral vestibular disorder and falls |
| 2. Evaluation of semicircular canal function by video head impulse test | |
| 3. Research on postural control using a stabilometer and motion capture | |
| 4. Research on changes in equilibrium due to exercise | |
| 5. Development of a new dynamic visual acuity test | |
| 6. Research on cardio ankle vascular index (CAVI) and prognosis of otolaryngological diseases | |
| 7. Analysis of nasal mucosa using narrow band imaging (NBI) |
| Supervisor(s) | Research areas / topics |
| Prof. Yuichi Hori, MD, PhD | 1. Ocular circulation and systemic disease |
| 2. Ocular surface barrier and homeostasis | |
| 3. New diagnostic technology of retinopathy of prematurity (ROP) | |
| 4. New diagnostic technology of ocular infection | |
| 5. Development of new devices for vitreoretinal surgery | |
| 6. Tear dynamics | |
| 7. Etiology of uveitis | |
| 8. New diagnostic technology of glaucoma | |
| Prof. Masahiro Ishida, MD, PhD | 1. Study on retinal morphology and visual function in macular disease |
| 2. Study on the mechanism of metamorphopsia | |
| 3. Development of new surgical techniques and devices for vitreoretinal surgery | |
| 4. Study on diagnosis of glaucoma | |
| 5. Study on three-dimensional image analysis of the fundus | |
| 6. Study on ocular blood flow |
Currently not available
Biological Response
| Supervisor(s) | Research areas / topics |
| Prof. Tetsuo Mikami, MD, PhD | 1. Clinicopathological analysis and molecular pathology of human cancer |
| 2. Stromal reaction in invasion and metastasis of carcinoma | |
| 3. Mechanism of carcinogenesis and cancer progression in chronic inflammation |
| Supervisor(s) | Research areas / topics |
| Prof. Naobumi Tochigi, MD, PhD | 1. Morphological analysis of lung cancer |
| 2. Histopathological analysis of thoracic neoplasms | |
| 3. Analysis of pathological images | |
| 4. Morphological analysis of deep-seated mycosis | |
| 5. Analysis of frequency of deep-seated mycosis | |
| Prof. Naoko Honma, MD, PhD | 1. Development of biomarkers to optimize treatment of breast cancer |
| 2. Role of estrogens in the pathobiology of cancers | |
| 3. Molecular mechanisms of cancers using patient-derived xenografts | |
| 4. Characteristics of cancers in older patients | |
| 5. Relationship between age-related diseases and estrogens |
| Supervisor(s) | Research areas / topics |
| Prof. Sohei Harada, MD, PhD | 1. Epidemiology, genetics, and clinical characteristics of multidrug-resistant organisms |
| 2. Pathogenesis of severe Klebsiella pneumoniae infections | |
| 3. Epidemiology, genetics, and clinical characteristics of Corynebacterium infections | |
| 4. Risk factors and clinical characteristics of infections in patients with solid tumors | |
| 5. Clinical application of novel microbiological diagnostic methods | |
| 6. Tracking of nosocomial transmission using next-generation sequencing | |
| 7. Host immune and metabolic responses following bacterial infections | |
| 8. Phenotypic diversity and pathogenicity of nontuberculous mycobacteria |
| Supervisor(s) | Research areas/topics |
| Prof. Motonari Kondo, MD, PhD | 1. Cytokine function during lymphocyte development |
| 2. Regulation of immune response by cytokines | |
| 3. Molecular mechanisms of T-cell differentiation and acquisition of immune tolerance | |
| 4. The role of acetylation in signaling molecules |
| Supervisor(s) | Research areas / topics |
| Prof. Kazuma Kishi, MD, PhD | 1. Mechanism of extracellular secretion of interleukin 33 by live cell imaging |
| 2. Frequency of interstitial lung disease with progressive fibrosis in ANCA-positive interstitial pneumonia | |
| 3. Diagnosis of humidifier lung and summer-type hypersensitivity pneumonitis using international guidelines | |
| 4. Antifibrotic agents and risk of lung cancer in idiopathic pulmonary fibrosis | |
| 5. Impact of pulmonary microbiome in Mycobacterium avium complex disease | |
| 6. Metabolome analysis of acute exacerbation of interstitial lung disease | |
| 7. MicroRNAs in serum exosomes in lung cancer with interstitial pneumonia | |
| 8. Phenotypes of humidifier lung and hypersensitivity pneumonitis by cluster analysis | |
| Prof. Hiroto Matsuse, MD, PhD | 1. Pathogenesis and treatment of refractory pulmonary infectious diseases |
| 2. Mechanisms and regulation of allergic airway inflammation in asthma | |
| 3. Peripheral airway obstruction in COPD | |
| 4. Acute exacerbation in chronic airway inflammation caused by infection | |
| 5. Pathogenesis and treatment of lung cancer | |
| 6. Epidemiology, diagnosis, and treatment of chronic cough in adults | |
| Prof. Kazutoshi Isobe, MD, PhD | 1. Efficacy and safety of bispecific T-cell engager antibodies in small cell lung cancer |
| 2. ICI efficacy and immune-related adverse events in lung cancer patients with autoimmune disease | |
| 3. Long non-coding RNAs in EGFR mutation–positive non-small cell lung cancer | |
| 4. Prospective study on serum biomarkers in pulmonary MAC disease | |
| 5. Drug-induced lung injury with inhaled liposomal amikacin | |
| 6. Dermatomyositis-specific autoantibodies in idiopathic interstitial pneumonia | |
| 7. Systemic sclerosis–specific autoantibodies in idiopathic interstitial pneumonia |
| Supervisor(s) | Research areas / topics |
| Prof. Atsushi Sano, MD, PhD | 1. Application of three-dimensional computed tomography in thoracic surgery |
| 2. Application of ultrasonography in thoracic surgery | |
| 3. Study on the influence of respiratory function on the perioperative period | |
| 4. Study on perioperative respiratory rehabilitation | |
| 5. Study on devices in thoracic surgery |
Currently not available
| Supervisor(s) | Research areas / topics |
| Prof. Toshihiro Nanki, MD, PhD | 1. Roles of bacterial blora in the pathogenesis of rheumatoid arthritis |
| 2. Pathogenesis of interstitial pneumonia complicated with rheumatic disease | |
| 3. intestinal flora in systemic lupus erythematosus | |
| 4. Pathogenesis of steroid-induced osteoporosis | |
| 5. Atherosclerosis in patients with rheumatoid arthritis | |
| 6. Aging and rheumatoid arthritis | |
| Prof. Hideto Kameda, MD, PhD | 1. Elucidation of the pathogenesis of rheumatic diseases ～Over-response to micro-injury hypothesis～ |
| 2. Study of molecular biological changes during the relapse of rheumatic diseases | |
| 3. Study on the treatment optimization of systemic lupus erythematosus and other intractable rheumatic diseases | |
| 4. Study on the relationship between the pathophysiology and images of arthritis | |
| 5. Enthesitis in spondyloarthritis and transcription factors |
Currently not available
| Supervisor(s) | Research areas / topics |
| Prof. Shinichi Takatsuki, MD, PhD | 1. Prognostic factors in acute Kawasaki disease |
| 2. Treatment strategies in acute Kawasaki disease | |
| 3. Multicenter registry of congenitial heart disease with pulmonary hypertension | |
| 4. Retrospective study of pregnant women with complex congenital heart disease | |
| 5. Treatment strategies in children with idiopathic and heritable PAH | |
| 6. Prognostic hemodynamic parameters in idiopathic and heritable PAH | |
| 7. Newest treatments in PAH | |
| 8. Managements of adult patients with childhood-onset disease | |
| Prof. Hideaki Kanemura, MD, PhD | 1. Investigation of QOL-related factors in childhood epilepsy |
| 2. Investigation of cognitive and behavioral problems in childhood epilepsy | |
| 3. Investigation of rational polypharmacological therapy for childhood epilepsy | |
| 4. Investigation of neurospychological aspects in childhood epilepsy | |
| 5. Investigation of seizure-recurrent factors in childhood epilepsy | |
| 6. Analysis of EEG characteristics in neurodevelopmental disorders | |
| 7. Investigation of biomarkers in neurodevelopmental disorders | |
| 8. Investigation of novel therapeutic approach for neurodevelopmental disorders | |
| 9. Electrophysiological research in pediatric neurological diseases |
Currently not available
| Supervisor(s) | Research areas / topics |
| Prof. Keiji Tanese, MD, PhD | 1. Elucidation of the mechanism of blister formation in autoimmune bullous diseases |
| 2. Investigation for multidisciplinary diagnosis and treatment of epidermolysis | |
| 3. Pathological and ultrastructural analysis of skin tumors | |
| 4. Analysis of gene expression and escape mechanisms of antitumor immunity in malignant skin | |
| 5. Surveillance of occupational skin disorders and causative allergens | |
| 6. Detection of strong sensitizers in the household commodities and their cross reactive | |
| 7. Evaluation of positive rates of the patch test using the Japanese standard allergens; surveillance and disease-oriented evaluation | |
| 8. Development of biomarkers indicating the disease activity of psoriasis | |
| 9. Development of biomarkers to predict response to treatment for atopic dermatitis | |
| Prof. Tetsuya Higuchi, MD, PhD | 1. Mechanism of the aggravation of psoriasis by adipocytokines |
| 2. Production of adipocytokines from subcutaneous tissue | |
| 3. Mechanism of skin eruption in autoimmune disease | |
| 4. Diagnosis of causative drug in patient with skin eruption | |
| 5. Analysis of skin eruption in inflammatory bowel disease | |
| 6. Comparison of ultrasonic image and histology in skin disease | |
| 7. Comparison of dermoscopy finding and histology in skin disease | |
| 8. Analysis of foot function in patients with epidermolysis bullosa simplex | |
| 9. Proteomic analysis of loquat allergens |
| Supervisor(s) | Research areas / topics |
| Prof. Koichi Nakajima, MD, PhD | 1. Development of the new biomarker for renal cell cancer |
| 2. Basic research for erectile dysfunction and epidemiological survey relationship between life-style disease and erectile dysfunction | |
| 3. Development of the simple and easy objectivity evaluation method for erectile function | |
| Prof. Hideyuki Kobayashi, MD, PhD | 1. Development of a new AI-based screening method for male infertility |
| 2. Research on human spermatogenesis and establishment of iPS cells | |
| 3. Research into generating germ cells from human iPS cells | |
| 4. Cross-sectional study of male infertility | |
| 5. Cross-sectional study of sexual dysfunction | |
| Prof. Noritoshi Sekido, MD, PhD | 1. Clinical research on urological cancers |
| 2. Physiological research on lower urinary tract function | |
| Prof. Hiroyoshi Suzuki, MD, PhD | 1. Search for novel biomarkers in urological tumors |
| 2. Elucidation of hormone refractory molecular mechanism of prostate cancer and therapeutic development | |
| 3. Development of predictive system for adverse events and prognosis of prostate cancer | |
| 4. Development of predictive models for clinical outcome of endoscopic surgery | |
| 5. Development of new equipment contributing to navigation and safety improvement of laparoscopic surgery | |
| 6. Basic and clinical studies on urinary voiding function | |
| 7. Investigation of postoperative biological change after the surgery for adrenal tumors | |
| 8. Development of novel graphic model in urological tumors | |
| 9. Clinical studies for heavy carbon ion beams for urological cancers |
| Supervisor(s) | Research areas / topics |
| Prof. Masaaki Hori, MD, PhD | (Diagnostic imaging) |
| 1. Assessment of perfusion and ventilation using dual energy CT for patients with COPD, Interstitial Pneumonitis: Assessment of perfusion using Lung PBV (perfused blood volume imaging) for patients with Pulmonary Thromboembolism | |
| 2. Evaluation of degenerative disease using advanced diffusion MR imaging: Evaluation of neural tissue by using quantitative MR imaging, Assessment of neuropsychiatric disorder and cerebral morphology | |
| 3. Evaluating the usefulness of fusion image in collaboration with nuclear medicine | |
| (Nuclear medicine) | |
| 1. Development and improvement of diagnosis method of brain disease with integrated image statistics analysis including nuclear medicine image and MRI | |
| Prof. Atsuro Terahara, MD, PhD | (Radiation oncology) |
| 1. Evaluation and optimization of dose distribution in high-precision radiotherapy | |
| 2. Acquisition and utilization of images for treatment planning in radiotherapy | |
| 3. Development and improvement of information system in radiotherapy | |
| Prof. Tatsuya Gomi, MD, PhD | 1. Clinical research on abdominal imaging |
| 2. Basic and clinical research on side effects of iodine contrast material | |
| 3. Research on new sequence of MRI | |
| 4. Research on new diagnostic method using workstation |
Socio-Environmental Medicine
| Supervisor(s) | Research areas / topics |
| Prof. Kunihiko Kurosaki, MD, PhD | 1. Individual identification based on the DNA polymorphism |
| 2. Genetic analyses of the human bone excavated from ancient remains | |
| 3. Medicolegal study of infectious diseases | |
| 4. Forensic pathology of sudden death from natural causes | |
| 5. Forensic toxicology of interaction of medical substances |
| Supervisor(s) | Research areas / topics |
| Prof. Yuji Nishiwaki, MD, PhD | 1. Environmental epidemiology |
| 2. Nutritional epidemiology | |
| 3. Social epidemiology | |
| 4. Life-course epidemiology | |
| 5. Epidemiology on aging | |
| 6. Clinical epidemiology, study of intractable disease | |
| 7. Study on occupational health | |
| 8. Development of mobile sensing device to measure personal light exposure |
| Supervisor(s) | Research areas / topics |
| Prof. Keiko Asakura, MD, PhD | 1. Preventive medicine and clinical epidemiology |
| 2. Descriptive epidemiology for nutrient intakes | |
| 3. Improvement of dietary habits | |
| 4. Maternal and child health/School health | |
| 5. Community health |
Currently not available
Currently not available
| Supervisor(s) | Research areas / topics |
| Prof. Yoshitaka Murakami, MD, PhD | 1. Meta-analysis of individual participants’ data |
| 2. Methodlogy and the practice in healthy life expectancy | |
| 3. Methodlogy of survey in epidemiologic research | |
| 4. Biostatistics for clinical research |
Currently not available
Currently not available
| Supervisor(s) | Research areas / topics |
| Prof. Takahiro Nemoto, MD, PhD | 1. Mental health and early intervention in the community-based integrated care system |
| 2. Cognitive rehabilitation for schizophrenia | |
| 3. Foreign residents’ mental health in Japan | |
| 4. Perinatal mental health | |
| 5. Psychotherapy such as Morita Therapy and Cognitive Behavior Therapy | |
| 6. Biological approach to mental disorders | |
| 7. Mental health in Adolescents and Young Adults | |
| 8. Implementation science in psychiatry | |
| 9. Child and adolescent liaison psychiatry |
| Supervisor(s) | Research areas/topics |
| Prof. Masahiro Hashizume, MD, PhD | 1. Somatosensory Amplification in Migraine |
| 2. The Cognition of Catastrophizing in Migraine | |
| 3. Stress Coping in Medication Overuse Headache | |
| 4. Depression among Community-dwelling Older Japanese Adults | |
| 5. Cerebral Near-Infrared Spectroscopy and Neuroimaging of Eating Disorder | |
| 6. Cognitive and Behavioral Therapy for Depression with Absences from Work |
| Supervisor(s) | Research areas / topics |
| Yoichi Nakamura | 1. Research on prognosis of cancer patients |
| 2. Research on quality-of-life measures of cancer patients | |
| 3. Research on end-of-life care | |
| 4. Research on spiritual pain and communication | |
| 5. Research on palliative care for neurological disorders | |
| 6. Research on palliative care for patients with renal failure |
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